Hepatology
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See the full rubric →One-year outcomes of hepatic artery stenosis after pediatric liver transplantation: Results from the international, multicenter HEPATIC registry.
Clinical takeawayAfter paediatric liver transplant, hepatic artery stenosis within 21 days carried 16% one-year graft loss versus 1% for later stenosis, and all deaths were in the early group, so early Doppler surveillance and prompt evaluation matter most. The registry cannot say whether antithrombotic therapy or endovascular treatment is better.
What it foundOne-year graft and patient survival after hepatic artery stenosis (HAS) were 93% and 96%, respectively, with early HAS (≤21 days post-pLT) associated with significantly higher graft loss compared to late HAS (16% vs. 1%; p < 0.001). All deaths occurred in the early HAS group.
ContextThis study confirms that HAS is a rare but serious complication post-pLT, with early HAS posing a higher risk. It refines understanding by showing comparable outcomes between antithrombotic therapy and EVT, challenging the assumption that EVT is superior.
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HEPATIC Study Group · Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · IF 4.2 · PubMed ↗