Hepatology
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See the full rubric →Abnormal left ventricular mass as a prognostic marker for outcomes in infants and children with cirrhosis.
Clinical takeawayConsider echocardiographic LVMI as a pretransplant risk marker in children with cirrhosis for perioperative planning. It is not a validated allocation tool; PELD/MELD still governs listing.
What it foundLeft ventricular mass index (LVMI) ≥ 88 g/m2.7, ≥ 91 g/m2.7, and ≥ 95 g/m2.7 independently predicted waitlist decompensation, composite serious adverse events, and mortality in children with cirrhosis, with OR 6.9 [CI 3,16] for LV hypertrophy.
ContextAbout 25% of children with cirrhosis had LV hypertrophy on echo and necropsy; cirrhotic cardiomyopathy remains undefined in children.
No standard claimed for this paper
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Bashir DA … Desai MS · Journal of Hepatology · IF 40.1 · PubMed ↗