← Issue №12/ week of Sep 20, 2026/Hepatology

Association Between Trajectories of Estimated Plasma Volume Status and All-Cause Mortality in Severe Liver Cirrhosis Patients.

From GI Signals issue №12: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Hepatology retrospective · n=2,146 · Sep 17, 2026 · Clin Transl Gastro · IF 3.4

Association Between Trajectories of Estimated Plasma Volume Status and All-Cause Mortality in Severe Liver Cirrhosis Patients.

New evidencecirrhosisbiomarkerepidemiology
What it foundIn ICU cirrhosis patients, a high-level slightly decreasing ePVS trajectory (traj 4) had 1.65x higher 28-day mortality vs low-level slow increase (traj 1) (HR 1.65, 95% CI 1.15-2.38).
ContextExtends prior evidence on ePVS as a prognostic marker by showing trajectory-specific mortality risks in ICU cirrhosis patients, refining risk stratification.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Yan P … Luo L · Clinical and Translational Gastroenterology · IF 3.4 · PubMed ↗Permalink
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