← Issue №16/ week of Oct 18, 2026/Endoscopy

Rapid versus slow puncture in endoscopic ultrasound-guided liver biopsy: a multicenter randomized crossover trial.

From GI Signals issue №16: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Endoscopy rct · n=62 · Oct 16, 2026 · Endoscopy · IF 11.8

Rapid versus slow puncture in endoscopic ultrasound-guided liver biopsy: a multicenter randomized crossover trial.

New evidenceEUSendoscopy qualitycomputer-aided detectionbiomarker
Clinical takeawayConsider using the rapid puncture technique for EUS-LB to improve specimen quality and diagnostic adequacy.
What it foundRapid puncture increased complete portal tracts by 2.39 (95%CI 1.50-3.27) and total specimen length by 15.19 mm (95%CI 9.65-20.74) vs slow puncture in EUS-LB.
ContextRefines current EUS-LB practice by demonstrating superior specimen quality with rapid puncture compared to the conventional slow technique.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Wu Y … Li B · Endoscopy · IF 11.8 · PubMed ↗Permalink
← Read the whole of issue №16 Every paper GI Signals surfaces gets a page like this one. All issues