← Issue №14/ week of Oct 4, 2026/Motility

PTSD Is Associated With Severity of Upper GI Symptoms in Patients With Gastroparesis.

From GI Signals issue №14: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Motility retrospective · n=207 · Oct 1, 2026 · Neurogastro Motil · IF 3.5

PTSD Is Associated With Severity of Upper GI Symptoms in Patients With Gastroparesis.

New evidencegastroparesis
Clinical takeawayConsider screening gastroparesis patients for PTSD using the PCL-5 (threshold >33) and addressing psychosocial factors in symptom management. Further exploration of trauma-focused therapy is suggested to assess its effects on improving symptoms.
What it found28% of gastroparesis patients screened positive for PTSD, which was associated with worse GI symptom severity (p < 0.01) but not gastric delay or accommodation.
ContextConfirms prior evidence linking PTSD to worse symptom severity in functional GI disorders and identifies reduced myoelectric activity in PTSD patients, but challenges assumptions about its impact on gastric motility.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Simons M … Lembo A · Neurogastroenterology and Motility · IF 3.5 · PubMed ↗Permalink
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