← Issue №13/ week of Sep 27, 2026/Endoscopy

Appendoscope-Assisted Endoscopic Retrograde Appendicitis Therapy Versus Antibiotic Monotherapy for Acute Uncomplicated Appendicitis.

From GI Signals issue №13: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Endoscopy retrospective · n=80 · Sep 23, 2026 · Dig Dis Sci · IF 2.5

Appendoscope-Assisted Endoscopic Retrograde Appendicitis Therapy Versus Antibiotic Monotherapy for Acute Uncomplicated Appendicitis.

New evidencecost-effectiveness
Clinical takeawayConsider ERAT as an alternative to antibiotic monotherapy for AUA in patients seeking to avoid surgery, weighing lower failure/recurrence against higher costs.
What it foundIn a retrospective study of acute uncomplicated appendicitis (AUA), ERAT reduced 1-year treatment failure (12.5% vs 42.5% with antibiotics) and recurrence (10.3% vs 30.3%), with faster pain relief (6h vs 48h) and shorter hospital stays (1d vs 5d), but higher costs (10,408.6 vs 2,868.9 CNY).
ContextRetrospective single-center data challenges antibiotic monotherapy for AUA by offering a non-surgical endoscopic option with better efficacy but higher costs.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Liu PC … Jing HZ · Digestive Diseases and Sciences · IF 2.5 · PubMed ↗Permalink
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