← Issue №12/ week of Sep 20, 2026/Nutrition

Divergent microbial preludes to necrotising enterocolitis defined by gut phages and bacterial resistomes.

From GI Signals issue №12: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Nutrition prospective cohort · n=129 · Sep 16, 2026 · Gut · IF 24.6

Divergent microbial preludes to necrotising enterocolitis defined by gut phages and bacterial resistomes.

Basic sciencebasic sciencetranslationalmicrobiomepediatric
Clinical takeawayNo clinical action yet: a mechanistic finding in preterm infants, focusing on microbial predictors of NEC.
What it foundEarly-onset NEC predicted by phage-bacterial interaction signatures (75% accuracy, 81% sensitivity); late-onset NEC predicted by antibacterial resistome profiles (83% accuracy).
ContextOpens a question on microbial predictors of NEC, distinct from current clinical predictors which are unreliable.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Zhang K … Dantas G · Gut · IF 24.6 · PubMed ↗Permalink
← Read the whole of issue №12 Every paper GI Signals surfaces gets a page like this one. All issues