Endoscopy
Signal score, how each part rates
ActionabilityPrevalenceStakesEvidence strengthNovelty
See the full rubric →AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection rate: a multicenter randomized controlled trial.
Clinical takeawayImplement AI-assisted second forward-view examination of the right colon during colonoscopy to improve adenoma detection, particularly for small, flat, and hard-to-reach lesions. This combined strategy was effective across all levels of endoscopist experience.
What it foundAI-assisted second forward-view examination of the right colon improved adenoma detection to 36.4% versus 27.9% (p = 0.03, absolute increase 8.5%), with greater detection of small, flat, and anatomically challenging lesions regardless of endoscopist experience.
ContextCombines two established detection strategies (AI assistance and reinspection) in a prospective RCT of right colon adenomas. Extends prior evidence that each approach independently improves adenoma detection by demonstrating their combined effect; the isolated contribution of the AI component versus the second-pass examination alone remains undetermined.
Refinessuggested applicable standard· U.S. Multi-Society Task Force on Colorectal Cancer (Rex DK, Boland CR, Dominitz JA, et al.), "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer," Gastroenterology, 2017
Decision at stakehow to perform colonoscopy to maximize adenoma detection in the right colon
U.S. Multi-Society Task Force on Colorectal Cancer (Rex DK, Boland CR, Dominitz JA, et al.), "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer," Gastroenterology, 2017 · reviewed 2026-07-23 ↗Begin average-risk colorectal cancer screening at age 45 using a patient-centered shared-decision modality choice, colonoscopy every 10 years (preferred) or annual FIT as Tier 1 options, with multi-target stool DNA every 3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 to 10 years as Tier 2 alternatives. A positive stool-based test requires diagnostic colonoscopy, and stool tests should not be ordered for patients who would decline follow-up colonoscopy. Generally stop at age 75 with individualized decisions for ages 76-85 and no screening beyond 85.
Nishikawa Y … Matsuda T · American Journal of Gastroenterology · IF 9.8 · PubMed ↗