← Issue №6/ week of Aug 9, 2026/Endoscopy

Diagnostic and Clinical Performance of Single-Use Versus Reusable Gastrointestinal Endoscopes: A Systematic Review and Meta-Analyses.

From GI Signals issue №6: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Endoscopy meta analysis · n=965,960 · Aug 7, 2026 · J Gastro Hep · IF 3.5

Diagnostic and Clinical Performance of Single-Use Versus Reusable Gastrointestinal Endoscopes: A Systematic Review and Meta-Analyses.

New evidencesystematic reviewmeta-analysisERCPendoscopy quality
Clinical takeawayMaintain current practice with reusable endoscopes and rigorous reprocessing protocols. Single-use devices offer no diagnostic or technical advantage, and documented infection risk from reusable endoscopes is low. For ERCP specifically, single-use duodenoscopes (EXALT Model D) required conversion to reusable in 7% of procedures, limiting their utility as a standalone option.
What it foundSingle-use endoscopes demonstrated similar or slightly reduced diagnostic accuracy and technical performance compared with reusable models; estimated infection risk from reusable endoscopes was 0.01% to 0.8%, although detection and reporting bias likely affected these estimates.
ContextPrior concerns about pathogen transmission drove interest in single-use endoscopes as a safer alternative. This meta-analysis confirms that properly reprocessed reusable endoscopes carry acceptably low infection risk (0.01-0.8%) and demonstrate comparable or superior diagnostic performance to single-use alternatives.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Tyldesley-Marshall N … Arasaradnam R · Journal of Gastroenterology and Hepatology · IF 3.5 · PubMed ↗Permalink
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