← Issue №5/ week of Aug 2, 2026/Pancreas/Biliary

Hospital Volume and Operative Mortality in Pancreaticoduodenectomy and Hepatectomy: Analysis of the National Clinical Database in Japan.

From GI Signals issue №5: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Pancreas/Biliary retrospective · n=74,446 · Aug 3, 2026 · J Hepatobil Pancreat Sci · IF 3.8

Hospital Volume and Operative Mortality in Pancreaticoduodenectomy and Hepatectomy: Analysis of the National Clinical Database in Japan.

New evidencehealth servicesepidemiologypancreatic cancerhepatocellular carcinoma
Clinical takeawayRefer patients undergoing pancreaticoduodenectomy or advanced hepatectomy to centers performing ≥50 advanced HBP procedures annually when feasible, as mortality is lower.
What it foundHospitals performing ≤19 advanced HBP procedures/year had significantly higher adjusted mortality for PD and hepatectomy compared to those performing 30-49 cases/year, while ≥50-case hospitals had significantly lower mortality. Mortality decreased with increasing volume and plateaued at approximately 50 annual procedures.
ContextConfirms volume-outcome relationship for complex HBP surgery, with procedure-specific mortality curves suggesting tailored quality metrics may be needed.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Shindo Y … Ohtsuka M · Journal of Hepato-Biliary-Pancreatic Sciences · IF 3.8 · PubMed ↗Permalink
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