World Endoscopy Organization Position Statements for the Role of Endoscopy on the Diagnosis and Treatment of Superficial Non-Ampullary Duodenal Epithelial Tumors: GI Signals

Endoscopy guideline · Aug 1, 2026 · Dig Endosc · IF 5.2

World Endoscopy Organization Position Statements for the Role of Endoscopy on the Diagnosis and Treatment of Superficial Non-Ampullary Duodenal Epithelial Tumors.

Guideline / reviewguidelineendoscopy qualitycomputer-aided detectionERCP

Clinical takeawayConsider endoscopic resection for SNADETs in elective cases with routine complete wound closure to mitigate complications; prioritize high-definition endoscopy and image-enhanced endoscopy (IEE) for diagnosis and characterization. Defer ER in high thromboembolic risk patients.

What it foundEndoscopic resection (ER) is the preferred approach for superficial non-ampullary duodenal epithelial tumors (SNADETs) in elective cases but carries substantial risk of complications, necessitating routine complete wound closure. High thromboembolic risk patients should defer ER.

ContextConfirms and refines current practice by endorsing ER for SNADETs while emphasizing the need for wound closure due to high complication risks and the importance of deferring ER in high thromboembolic risk patients, addressing prior geographic variability in management.

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Arantes VN … WEO Stomach and Duodenal Diseases Committee · Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society · IF 5.2 · PubMed ↗Permalink