Endoscopy
Signal score, how each part rates
ActionabilityPrevalenceStakesEvidence strengthNovelty
See the full rubric →Computer-aided quality assurance versus standard colonoscopy: A systematic review and meta-analysis of randomized-controlled trials.
Clinical takeawayConsider adopting CAQ systems for colonoscopy to improve detection of adenomas and advanced adenomas, given the significant increase in ADR and AADR.
What it foundComputer-aided quality assurance (CAQ) increased adenoma detection rate (ADR) by 43% (RR 1.43, 95% CI 1.17-1.73) and advanced ADR (AADR) by 54% (RR 1.54, 95% CI 1.26-1.87) compared to standard colonoscopy, though findings for AADR and adenocarcinoma detection rate (ACDR) should be interpreted with caution due to low event rates.
ContextThis meta-analysis supports the use of CAQ over standard colonoscopy in average-risk patients, refining current practice by demonstrating improved detection rates for clinically significant lesions, with caution advised for interpreting AADR and ACDR due to low event rates.
Refinessuggested applicable standard· U.S. Multi-Society Task Force on Colorectal Cancer (Rex DK, Boland CR, Dominitz JA, et al.), "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer," Gastroenterology, 2017
Decision at stakethe choice of colonoscopy as the preferred screening modality for colorectal cancer
U.S. Multi-Society Task Force on Colorectal Cancer (Rex DK, Boland CR, Dominitz JA, et al.), "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer," Gastroenterology, 2017 · reviewed 2026-07-23 ↗Begin average-risk colorectal cancer screening at age 45 using a patient-centered shared-decision modality choice, colonoscopy every 10 years (preferred) or annual FIT as Tier 1 options, with multi-target stool DNA every 3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 to 10 years as Tier 2 alternatives. A positive stool-based test requires diagnostic colonoscopy, and stool tests should not be ordered for patients who would decline follow-up colonoscopy. Generally stop at age 75 with individualized decisions for ages 76-85 and no screening beyond 85.
Cold KM … Konge L · Endoscopy · IF 11.8 · PubMed ↗