Endoscopy
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See the full rubric →Colonoscopy complications and associated costs and mortality in a Swedish colorectal cancer screening program.
Clinical takeawayContinue recommending colonoscopy as the preferred screening modality, as real-world data confirm complications occur in <1% of screening procedures with no increase in mortality and minimal program costs
What it foundBleeding in 47/10,000 screening colonoscopies (RR 52.6); any complication in 86/10,000 (0.86%); no mortality increase vs matched controls (RR 0.4, 95%CI 0.1-1.0); excess healthcare cost €32.88 per procedure.
ContextThis literature reports real-world complication rates and healthcare costs associated with screening colonoscopy in a large population cohort, with complications measured within 7 days of the procedure.
Reinforcessuggested applicable standard· U.S. Multi-Society Task Force on Colorectal Cancer (Rex DK, Boland CR, Dominitz JA, et al.), "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer," Gastroenterology, 2017
Decision at stakeUse colonoscopy every 10 years as the preferred Tier 1 screening option for average-risk individuals starting at age 45
U.S. Multi-Society Task Force on Colorectal Cancer (Rex DK, Boland CR, Dominitz JA, et al.), "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer," Gastroenterology, 2017 · reviewed 2026-07-23 ↗Begin average-risk colorectal cancer screening at age 45 using a patient-centered shared-decision modality choice, colonoscopy every 10 years (preferred) or annual FIT as Tier 1 options, with multi-target stool DNA every 3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 to 10 years as Tier 2 alternatives. A positive stool-based test requires diagnostic colonoscopy, and stool tests should not be ordered for patients who would decline follow-up colonoscopy. Generally stop at age 75 with individualized decisions for ages 76-85 and no screening beyond 85.
Torbjörnsson E … Blom J · Endoscopy · IF 11.8 · PubMed ↗