← Issue №4/ week of Jul 26, 2026/Endoscopy

Neoplastic recurrence after colorectal endoscopic submucosal dissection at scheduled endoscopic surveillance: a systematic review and meta-analysis.

From GI Signals issue №4: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Endoscopy meta analysis · n=5,306 · Jul 27, 2026 · Endoscopy · IF 11.8

Neoplastic recurrence after colorectal endoscopic submucosal dissection at scheduled endoscopic surveillance: a systematic review and meta-analysis.

New evidencemeta-analysisESDdysplasiacolorectal cancer
Clinical takeawayConsider extending surveillance intervals up to 5 years for low-risk patients (R0 resection, favorable histology), as recurrence is rare and mostly due to metachronous lesions.
What it foundNeoplastic recurrence after colorectal ESD was 1.2% at 1 year, 1.4% at 3 years, and 1.9% at 5 years, with malignant recurrence rare (0.2%) and confined to noncurative resections or deep submucosal invasion.
ContextConfirms low recurrence risk after ESD, refining post-ESD surveillance strategies by identifying low-risk patients who may benefit from less frequent monitoring.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Ramai D … Jacques J · Endoscopy · IF 11.8 · PubMed ↗Permalink
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