{
  "version": "https://jsonfeed.org/version/1.1",
  "title": "GI Signals - Endoscopy",
  "home_page_url": "https://siftingsignal.com/gisignals/",
  "feed_url": "https://siftingsignal.com/gisignals/feed/endoscopy.json",
  "description": "Endoscopy papers worth knowing in GI this week. A SiftingSignal publication.",
  "items": [
    {
      "id": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42442706",
      "url": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42442706",
      "title": "Computer-aided quality assurance versus standard colonoscopy: A systematic review and meta-analysis of randomized-controlled trials.",
      "date_published": "2026-07-18T20:04:34Z",
      "content_text": "Endoscopy. Consider adopting CAQ systems for colonoscopy to improve adenoma detection, particularly in settings where ADR is suboptimal. The trade-off is a modest increase in withdrawal time (0.63 minutes). Interpret AADR and ACDR improvements cautiously due to low event rates."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42447876",
      "url": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42447876",
      "title": "Curriculum on management of acute upper gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.",
      "date_published": "2026-07-18T20:04:34Z",
      "content_text": "Endoscopy. GI clinicians involved in training should ensure trainees meet ESGE's structured competency framework before managing UGIB, including simulator training and supervised procedures. No direct clinical action for non-trainers: this is a guideline for endoscopy education."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42448239",
      "url": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42448239",
      "title": "Long term follow-up from the Barrett's esophagus screening trial 3 (BEST3) demonstrates high negative predictive value of capsule-sponge-Trefoil-factor-3 (TFF3) test for esophageal adenocarcinoma.",
      "date_published": "2026-07-18T20:04:34Z",
      "content_text": "Gastroenterology. Consider using the capsule-sponge-TFF3 test as a non-invasive screening tool to rule out esophageal adenocarcinoma in patients at risk for Barrett's esophagus, pending further validation in broader populations."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42456983",
      "url": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42456983",
      "title": "Advanced and Salvage Techniques for Difficult Biliary Cannulation in ERCP: A Randomized Trial of Outcomes and Efficacy.",
      "date_published": "2026-07-18T20:04:34Z",
      "content_text": "Gastrointestinal endoscopy. For difficult biliary cannulation in patients with both malignant and benign biliary obstruction, consider double-guidewire (DGT), trans-pancreatic sphincterotomy (TPS), or precut fistulotomy as equally effective salvage options, but weigh DGT's lower pancreatitis risk (10%) against precut's reduced contrast use and higher pancreatitis risk (24%). Base choice on anatomy, operator skill, and resource availability."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42462747",
      "url": "https://siftingsignal.com/gisignals/2026-W29/#card-pmid-42462747",
      "title": "Artificial intelligence-assisted detection and optical differentiation of colorectal lesions in Lynch syndrome surveillance (CADLY2): a multicentre, open-label, randomised controlled superiority trial.",
      "date_published": "2026-07-18T20:04:34Z",
      "content_text": "The lancet. Gastroenterology & hepatology. Consider using AI-assisted colonoscopy (e.g., CAD EYE) during Lynch syndrome surveillance to improve adenoma detection, acknowledging potential bias from unblinded endoscopists."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-41701117",
      "url": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-41701117",
      "title": "Dysplasia detection using high-definition scopes with dye vs virtual chromoendoscopy in IBD: A meta-analysis of randomized clinical trials.",
      "date_published": "2026-07-09T16:47:07Z",
      "content_text": "Inflammatory bowel diseases. No need to prefer dye over virtual chromoendoscopy for dysplasia detection in IBD surveillance, as both methods perform similarly. Choose based on availability, cost, or operator preference."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42365851",
      "url": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42365851",
      "title": "Computer-aided detection in surveillance colonoscopy: a population-based randomized trial.",
      "date_published": "2026-07-09T16:47:07Z",
      "content_text": "Endoscopy. Consider CADe for endoscopists with lower baseline ADR (<54.5%) in surveillance colonoscopy, as it improves detection in this subgroup. For high-performing endoscopists, CADe does not provide additional benefit."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42366841",
      "url": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42366841",
      "title": "Methodology Assessment of Endoscopic Ultrasound Radiofrequency Ablation (EUS-RFA) for Pancreatic Neoplasms: Results From an International Survey.",
      "date_published": "2026-07-09T16:47:07Z",
      "content_text": "Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. EUS-RFA for pancreatic neoplasms remains non-standardized outside insulinoma; indications, antibiotic prophylaxis, power settings, and follow-up vary widely, so it stays investigational pending consensus, with no immediate practice change."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42383968",
      "url": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42383968",
      "title": "Adverse events associated with endoscopic retrograde cholangiopancreatography (ERCP) and ERCP-related procedures.",
      "date_published": "2026-07-09T16:47:07Z",
      "content_text": "Gastrointestinal endoscopy. Apply ASGE ERCP adverse-event guidance now: routine rectal NSAID (indomethacin or diclofenac 100 mg) for post-ERCP pancreatitis prophylaxis and prophylactic pancreatic-duct stenting in high-risk cases, plus aggressive periprocedural hydration."
    },
    {
      "id": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42409294",
      "url": "https://siftingsignal.com/gisignals/2026-W26/#card-pmid-42409294",
      "title": "Single-blinded randomized controlled trial comparing the effect of underwater versus carbon dioxide insufflation during peroral endoscopic myotomy on post-procedural pain (U-POEM trial).",
      "date_published": "2026-07-09T16:47:07Z",
      "content_text": "Gastrointestinal endoscopy. Underwater immersion (U-POEM) may reduce post-procedural pain and opioid requirements vs CO2-POEM in achalasia type I/II, though larger trials are needed before protocol changes."
    }
  ]
}